Product ID:ACETONE ACS REAGENT, A4206
MSDS Date:07/01/1999
FSC:6810
NIIN:00N092611
Status Code:A
MSDS Number: CJTSF

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL, RAT) 5800 MG/KG

CAS: 67-64-1

RTECS: AL3150000

OSHA PEL 2400 MG/M3;1000 PPM

ACGIH TLV: 1780 MG/M3;750 PPM

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: MAY BE HARMFUL BY
INHALATION, INGESTION, OR SKIN ABSORPTION. CAUSES SEVERE EYE
IRRITATION. CAUSES SKIN IRRITATION. MATERIAL IS IRRITATING TO
MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT . CAUSES DERMATITIS.
TARGET ORGANS: LIVER, KIDNEYS. SEE ALSO TOXICOLOGICAL INFORMATION.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING
OF THE EYES BY SEPARATING THE EYELIDS WITH FINGERS. SKIN: FLUSH
SKIN WI TH WATER. INHALATION: IF INHALED, REMOVE TO FRESH AIR. IF
NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS
DIFFICULT, GIVE OXYGEN. INGESTION: IF SWALLOWED, WASH OUT MOUTH
WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. REMOVE
AND WASH CONTAMINATED CLOTHING PROMPTLY.

Flash Point:=-17.2C, 1.F
Autoignition Temp:=465.C, 869.F
Lower Limits:2%
Upper Limits:13%
Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE
FOAM. WATER MAY BE EFFECTIVE FOR COOLING, BUT MAY NOT EFFECT
EXTINGUISHMENT.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:EXTREMELY FLAMMABLE. VAPOR MAY TRAVEL
CONSIDERABLE DISTANCE TO SOURCE OF IGNITION AND FLASH BACK.

Spill Release Procedures:EVACUATE AREA. SHUT OFF ALL SOURCES OF
IGNITION. WEAR NIOSH APPROVED SELF-CONTAINED BREATHING APPARATUS,
RUBBER BOOTS AND HEAVY RUBBER GLOVES. COVER WITH AN ACTIVATED
CARBON ABSORBENT, TAKE UP AND PLA CE IN CLOSED CONTAINERS.
TRANSPORT OUTDOORS. VENTILATE AREA AND WASH SPILL SITE AFTER
MATERIAL PICKUP IS COMPLETE. WASTE #U002.

Handling and Storage Precautions:KEEP TIGHTLY CLOSED. KEEP AWAY FROM
HEAT, SPARKS AND OPEN FLAME. STORE IN A COOL, DRY PLACE.
Other Precautions:DO NOT BREATHE VAPOR. DO NOT GET IN EYES, ON SKIN, ON
CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. WASH THOROUGHLY
AFTER HANDLING. SEVERE EYE IRRITANT.

Respiratory Protection:NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . FACESHIELD (8-INCH MINIMUM).
Supplemental Safety and Health
STATE REG INFO: EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, DECEMBER
1998. NIOSH ANALYTICAL METH, 1994: KETONES I, 1300. NIOSH
ANALYTICAL METH, 1996: VOC, 2549, NTP TOXICITY STUDIES, RPT#
TOX-03, NOV EMBER 1998. OSHA ANALYTICAL METHOD #ID-69.

Boiling Pt:=56.C, 132.8F
Melt/Freeze Pt:=-94.C, -137.2F
Vapor Pres:184 MM 20C;400 MM 39.5C
Vapor Density:2
Spec Gravity:0.791
Appearance and Odor:COLORLESS LIQUID.

BASES, OXIDIZING AGENTS, REDUCING AGENTS.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE.

Waste Disposal Methods:BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER BUT EXERT EXTRA CARE IN IGNITING AS THIS
MATERIAL IS HIGHLY FLAMMABLE. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGUL ATIONS. RCRA WASTE NUMBER: U002.

Toxicological Information:RTECS #: AL3150000 ACETONE. IRRITATION DATA:
EYE-HMN 500 PPM JIHTAB 25,282,1943. SKN-RBT 395 MG OPEN MLD UCDS
5/7/1970. SKN-RBT 500 MG/24H MLD 85JCAE -,280,1986. EYE-RBT 20 MG
SEV AJOPAA 29,1363,1946. EYE-RBT 20 MG/24H MOD 85JCAE -,280,1986.
TOXICITY DATA: UNR-MAN LD50: 1159 MG/KG 85DCAI 2,73,1970. ORL-RAT
LD50: 5800 MG/KG JTEHD6 15,609,1985. IHL-RAT LC50: 50100 MG/M3/8H
AIHAAP 20,364,1959. IVN-RA T LD50: 5500 MG/KG NPIRI 1,1,1974.
ORL-MUS LD50: 3 GM/KG PCJOAU 14,162,1980. IHL-MUS LC50: 44 GM/M3/4H
CUTOEX 1,47,1993. IPR-MUS LD50: 1297 MG/KG SCCUR -,1,1961. ORL-RBT
LD50: 5340 MG/KG FAONAU 48A,86 ,1970. (OTHER INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAIL. OTHER INFO: CONTRACTION OR SPASTICITY).
LUNGS, THORAX OR RESPIRATION (RESP DEPRES; OTHER CHANGES). KIDNEY,
URETER, BLADDER (RENAL FUNCT TESTS DEPRESSED). EFTS ON FERTILITY
(POST-IM PLANTATION MORTALITY). ONLY SELECTED REGISTRY OF TOXIC
EFTS OF CHEM SUSBTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL
ENTRY IN RTECS FOR COMPLETE INFO. FED REG INFO: (GEN INDU): 8H TWA
1000 PPM (2 400 MG/M3) CFRGBR 29,1910.1000,1994. OSHA PEL
(CONSTRUC): 8H TWA 1000 PPM (2400 MG/M3) CFRGBR 29,1926.55,1994.
OSHA PEL (SHIPYARD): 8H TWA 1000 PPM (2400 MG/M3) CFRGBR
29,1915.1000,1993. OSHA PEL (FED CONT): 8H TWA (TRANSPORT INFO)

Transport Information:CNTCT SIGMA CHEM COMPANY FOR TRANPORTATION INFO.
ECOLOGICAL INFO: 1000 PPM (2400 MG/M3) CFRGBR 41,50-204.50,1994.
OEL-AUSTRALIA:TWA 500 PPM (1185 MG/M3); STEL 1000 PPM JAN 1993.
OEL-AUSTRIA:TWA 750 PP M (1780 MG/M3) JAN 1993. OEL-BELGIUM:TWA 750
PPM (1780 MG/M3); STEL 1000 PPM JAN 1993.OEL-DENMARK:TWA 250 PPM
(600 MG/M3) JAN 1993. OEL-FINLAND: TWA 500 PPM (1200 MG/M3); STEL
625 PPM (1500 MG/M3) JAN 1993. OEL-FRANCE:TWA 750 PPM (1800 MG/M3)
JAN 1993. OEL-GERMANY:TWA 1000 PPM (2400 MG/M3) JAN 1993.
OEL-HUNGARY:TWA 600 MG/M3; STEL 1200 MG/M3 JAN 1993. OEL-INDIA:TWA
750 PPM (1780 MG/M3); STEL 1000 PPM (2375 MG/M3) (SARA REG INFO)

SARA Title III Information:N/P. TRANSPORT INFO: JAN 1993. OEL-JAPAN:TWA
200 PPM (470 MG/M3) JAN 1993. OEL-NETHERLANDS:TWA 750 PPM (1780
MG/M3) JAN 1993. OEL-PHILIPPINES:TWA 1000 PPM (2400 MG/M3) JAN
1993. OEL-POLAND:TWA 200 MG/ M3 JAN 1993. OEL-RUSSIA:TWA 200 PPM;
STEL 200 MG/M3 JAN 1993. OEL-SWEDEN:TWA 250 PPM (600 MG/M3); STEL
500 PPM (1200 MG/M3) JAN 1993. OEL-SWITZERLAND:TWA 750 PPM (1780
MG/M3) JAN 1993. OEL-TURKET:TWA 1000 PPM (2400 MG/M3) JAN 1993.
OEL-UNITED KINGDOM:TWA 1000 PPM (2400 MG/M3); STEL 1250 PPM JAN
1993. OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV. OEL
IN NEW ZEALAND, SINGAPORE, VIETNAM C HECK ACGIH TLV. (STATE REG
INFO)
Federal Regulatory Information:EUROPEAN INFO: EC INDEX NO:
606-001-00-8. HIGHLY FLAM. IRRITANT. R 11 HIGHLY FLAM. S 9 KEEP
CNTNR IN WELL-VENTD PLACE. S 16 KEEP AWAY FROM SOURCES OF IGNIT -
NO SMKNG. S 23 DO NOT BREATHE VAP. S 33 TA KE PRECAUTIONARY
MEASURES AGAINST STATIC DISCHARGES. REVIEWS, STDDS & REGS: OEL=MAK.
ACGIH TLV-NOT CLASSIFIABLE AS HUMAN CARCIN DTLVS TLV/BEI,1997.
ACGIH TLV-STEL 1782 MG/M3 (750 PPM) DTLVS TLV/BEI, 1 997. ACGIH
TLV-TWA 1188 MG/M3 (500 PPM) DTLVS TLV/BEI,1977. EPA FIFRA 1988
PESTICIDE SUBJECT TO REGI STRATION OR RE-REGISTRATION FEREAC
54,7740,1989. MSHA STANDARD-AIR:TWA 1000 PPM (2400 MG/M3) DTLVS
3,3,1971. OSHA PEL (ECOLOGICAL INFO)
State Regulatory Information:N/P. SARA REG INFO: NIOSH REL TO
ACETONE-AIR: 10H TWA 250 PPM. NIOSH DHHS #92-100,1992. NOHS 1974:
HZD 02820; NIS 350; TNF 99713; NOS 188; TNE 1287794. NOES 1983: HZD
02820; NIS 358; TNF 97342; NOS 21 5; TNE 1740164; TFE 540313. EPA
GENETOX PROGRAM 1988, NEG: SHE-CLONAL ASSAY; CELL TRANSFORM-MOUSE
EMBRYO. EPA GENETOX PROGRAM 1988, NEG: CELL TRANSFORM-RLV F344 RAT
EMBRYO. EPA GENETOX PROGRAM 1988, N EG: IN VITRO
CYTOGENETICS-NONHUMAN. EPA GENETOX PROGRAM 1988, NEG: HISTIDINE
REVERSION-AMES TEST; IN VITRO SCE-NONHUMAN. EPA TSCA SECTION 8(B)
CHEM INVENTORY. EPA TSCA SECTION 8(D) UNPUB HLTH/SFTY STUDIES ON
EPA IRIS DATABASE. (SUPDAT)